What Techniques are Used in Genomic and Molecular Profiling?
Several advanced techniques are used for profiling, including:
Next-Generation Sequencing (NGS): Allows comprehensive analysis of the cancer genome, identifying mutations, copy number variations, and other genetic alterations. Whole Exome Sequencing (WES): Focuses on sequencing the protein-coding regions of the genome, which are most likely to contain clinically relevant mutations. RNA Sequencing (RNA-Seq): Analyzes gene expression levels and detects fusion genes and alternative splicing events. Proteomics: Studies the protein content of cancer cells, providing insights into protein expression, modifications, and interactions.
