What Types of Cancer are Most Affected by TNF Receptor Signaling?
TNF receptor signaling is particularly significant in cancers characterized by chronic inflammation, such as colorectal cancer, hepatocellular carcinoma, and certain types of leukemia and lymphoma. In these cancers, TNF can contribute to an inflammatory microenvironment that supports tumor growth and progression. However, the exact role of TNF signaling can vary widely among different cancers and even among patients with the same type of cancer.
