What Types of Cancers are Associated with the FA Pathway?
Besides AML and squamous cell carcinomas, defects in the FA pathway have been linked to breast, ovarian, and other solid tumors. Research indicates that BRCA1 and BRCA2, which are involved in breast and ovarian cancer susceptibility, are part of the FA pathway. This connection underscores the pathway's broader relevance to cancer biology beyond traditional FA-associated malignancies.
