What Types of Chromosomal Abnormalities are Common in Cancer?
Various types of chromosomal abnormalities are frequently observed in cancers:
Deletions: Loss of a chromosome segment, potentially removing crucial genes. Duplications: Extra copies of chromosome segments, leading to gene overexpression. Inversions: Reversed orientation of a chromosome segment, which can disrupt gene function. Translocations: Rearrangement between non-homologous chromosomes, often producing fusion genes. Aneuploidy: Abnormal number of chromosomes, resulting in genomic instability.
