What Types of Models are Used in Preclinical Cancer Studies?
Various models are employed in preclinical studies to simulate human cancer, including:
Cell Lines:Cancer cell lines grown in culture are utilized for high-throughput screening of potential treatments. Animal Models:Mouse models are commonly used due to their genetic and biological similarities to humans. Both genetically engineered mice and xenograft models (where human cancer cells are implanted in mice) are prevalent. Organoids: These are 3D structures grown from stem cells that mimic the architecture and function of real organs, providing a more accurate representation of tumor behavior.
