What Types of Solubilizing Agents Are Used in Cancer Therapy?
Several types of solubilizing agents are employed in cancer therapy, including:
Surfactants: These include polysorbates and polyethylene glycol (PEG), which are commonly used to enhance the solubility of hydrophobic drugs. Polymers: Polyvinylpyrrolidone (PVP) and PEGylated compounds are used to improve the solubility and stability of drugs. Cyclodextrins: These cyclic oligosaccharides form inclusion complexes with hydrophobic drugs, increasing their solubility and stability. Lipid-based formulations: Liposomes and lipid nanoparticles are used to encapsulate hydrophobic drugs, enhancing their solubility and delivery to cancer cells.
