Which Factors Contribute to DNA Degradation in Cancer?
Several factors contribute to DNA degradation in cancer:
Oxidative stress: Reactive oxygen species (ROS) produced during metabolic processes can damage DNA. Inflammation: Chronic inflammation can lead to the production of enzymes and free radicals that degrade DNA. Radiation: Both ionizing and non-ionizing radiation can cause breaks in the DNA strands. Chemical exposure: Carcinogens such as tobacco smoke and asbestos can induce DNA damage. Defective DNA repair mechanisms: Mutations in genes responsible for DNA repair can exacerbate DNA degradation.
