Which Glucose Transporters are Most Relevant in Cancer?
GLUT1 is the most commonly overexpressed glucose transporter in various cancers, including breast, colorectal, and lung cancers. Its overexpression is often correlated with poor prognosis and increased tumor aggressiveness. Other GLUTs, such as GLUT3, GLUT4, and GLUT12, are also implicated in cancer metabolism, albeit to a lesser extent.
