Why are IDH1 Mutations Significant in Cancer Diagnosis?
Detection of IDH1 mutations can be critical for the diagnosis and classification of certain cancers. For instance, in gliomas, the presence of an IDH1 mutation is associated with a better prognosis and can help differentiate between glioblastomas and lower-grade gliomas. Similarly, in AML, IDH1 mutations signify distinct clinical and biological features that can influence treatment strategy.
