Why are miRNA Inhibitors Important in Cancer Therapy?
Given the pivotal role of miRNAs in cancer, miRNA inhibitors offer a promising therapeutic approach. By inhibiting oncogenic miRNAs, these inhibitors can potentially restore normal gene expression and cellular function, thereby inhibiting cancer progression. For instance, targeting oncomiRs that suppress tumor suppressor genes can reinstate the function of these critical genes, leading to reduced tumor growth and increased sensitivity to conventional therapies.