Why is Intravasation Important in Cancer Progression?
Intravasation is a critical step in the metastatic cascade, which significantly contributes to cancer morbidity and mortality. Once cancer cells enter the bloodstream, they can travel to distant organs and form metastatic colonies. This dissemination is often responsible for the spread of cancer to vital organs like the lungs, liver, and brain, making it challenging to treat. Understanding the mechanisms of intravasation can help in developing therapeutic strategies to inhibit metastasis and improve patient outcomes.