Why is Pyrosequencing Important in Cancer Research?
Pyrosequencing plays a crucial role in cancer research for several reasons: 1. Detection of Mutations: It allows for the precise detection of mutations in cancer-related genes, which can be critical for diagnosing specific types of cancer. 2. Quantification of Methylation: It is used to quantify DNA methylation, a key epigenetic modification that can affect gene expression in cancer cells. 3. Assessment of Heterogeneity: The technology can assess the genetic heterogeneity within a tumor, helping to understand the complexity and evolution of cancer.
