metabolism of chemotherapeutic agents

Why is Understanding Drug Metabolism Important in Cancer Therapy?

Understanding drug metabolism is essential for several reasons:
Optimizing Dosage: Knowledge of metabolic pathways helps in determining appropriate dosages to maximize efficacy while minimizing toxicity.
Predicting Drug Interactions: Understanding metabolism aids in anticipating potential drug-drug interactions that could affect treatment outcomes.
Personalized Medicine: Genetic testing for metabolic enzyme polymorphisms can guide personalized treatment plans, improving patient outcomes.
Managing Side Effects: Awareness of metabolic pathways can help in managing and mitigating adverse effects associated with chemotherapy.

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