Split dose regimens are employed for several reasons: - Reduced Side Effects: By giving smaller doses, the body can better tolerate the treatment, reducing the severity of side effects such as nausea, fatigue, and organ toxicity. - Enhanced Efficacy: Smaller, more frequent doses can maintain a consistent level of the drug in the bloodstream, potentially improving its effectiveness against cancer cells. - Better Recovery: Dividing the dose allows normal cells some time to recover between treatments, which can be crucial for patients with compromised health.