Yes, several treatments aim to reduce the levels or effects of DHT to manage prostate cancer. These include:
5-alpha reductase inhibitors: Drugs like finasteride and dutasteride inhibit the enzyme 5-alpha reductase, which converts testosterone to DHT, thus lowering DHT levels. Androgen receptor antagonists: Medications such as flutamide, bicalutamide, and enzalutamide block the action of androgens, including DHT, at the cellular level. LHRH agonists and antagonists: These drugs reduce the production of testosterone, subsequently decreasing DHT levels.
