While CDKN1C is primarily recognized as a tumor suppressor, in certain contexts, it may exhibit oncogenic properties. The dual role of CDKN1C is not entirely understood, but it is hypothesized that its expression levels and cellular context determine its function. Overexpression of CDKN1C in some tumors can lead to enhanced survival signaling, resistance to apoptosis, and promotion of a stem-like state, contributing to tumor progression and resistance to therapy.
