Can Integrins Serve as Biomarkers for Cancer Diagnosis and Prognosis?
Integrins hold promise as biomarkers for cancer diagnosis and prognosis. Changes in integrin expression levels and patterns can indicate tumor presence and progression. For instance, elevated levels of αvβ3 integrin are associated with aggressive tumors and poor prognosis in various cancers, including melanoma and breast cancer. Monitoring integrin expression can aid in early detection, assessment of disease stage, and prediction of treatment response.
