Can SMAD7 Serve as a Biomarker for Cancer Diagnosis or Prognosis?
Yes, SMAD7 has potential as a biomarker for cancer diagnosis and prognosis. For instance, elevated levels of SMAD7 mRNA or protein in tumor tissues can indicate a poor prognosis in colorectal cancer. Similarly, the detection of SMAD7 genetic alterations or expression patterns in blood or tissue samples could assist in the early diagnosis of certain cancers.