Can targeting the tumor microenvironment improve cancer treatment outcomes?
Yes, targeting the tumor microenvironment can potentially improve cancer treatment outcomes. Therapeutic strategies that disrupt the interactions between cancer cells and their microenvironment can inhibit tumor growth and metastasis. For example, anti-angiogenic therapies aim to cut off the tumor's blood supply, while drugs targeting CAFs can disrupt their supportive role. Additionally, modulating the immune microenvironment with immunotherapies can enhance the body's natural ability to fight cancer. Combining these approaches with traditional treatments like chemotherapy and radiation may lead to more effective and durable responses.
