RAD50 mutations can be detected using various genetic testing techniques. Next-generation sequencing (NGS) is commonly employed to identify mutations across the RAD50 gene with high accuracy and speed. Other methods include Sanger sequencing, which is often used for validation, and multiplex ligation-dependent probe amplification (MLPA), which can detect large deletions or duplications in the gene. Early detection of RAD50 mutations can be crucial for risk assessment and management in patients prone to cancer.
