The activation of T cells involves multiple steps. First, antigen-presenting cells (APCs) such as dendritic cells capture and process antigens from cancer cells. These antigens are then presented on the APC surface through molecules called Major Histocompatibility Complex (MHC). When a T cell receptor (TCR) on the surface of a T cell recognizes and binds to the antigen-MHC complex, it initiates a series of intracellular signaling cascades that activate the T cell.