Overcoming drug inactivation involves several strategies:
Combination Therapy: Using multiple drugs with different mechanisms can help overcome resistance. Inhibitors: Specific inhibitors can target enzymes or efflux pumps responsible for drug inactivation. Personalized Medicine: Tailoring treatment based on the genetic profile of the tumor can improve outcomes. Nanotechnology: Nanoparticles can be used to deliver drugs directly to cancer cells, bypassing inactivation mechanisms.