How Do MHC Class I Molecules Work in Cancer Surveillance?
MHC Class I molecules play a vital role in cancer surveillance by displaying peptides derived from intracellular proteins on the cell surface. If these peptides are recognized as foreign or abnormal by CTLs, the CTLs can initiate an immune response to destroy the cancerous or infected cells. This process is part of the body's natural defense mechanism against the development and spread of tumors.