How Do Tumor Cells Exploit Pro Inflammatory Signals?
Tumor cells can hijack pro inflammatory signals to create a supportive microenvironment. For example, cancer cells can produce cytokines and chemokines that recruit immune cells like macrophages and neutrophils, which can be reprogrammed to support tumor growth instead of attacking it. Tumor-associated macrophages (TAMs) can release growth factors and proteases that remodel the extracellular matrix, facilitating invasion and metastasis.
