There are several platforms for long read sequencing, the most notable being Pacific Biosciences (PacBio) and Oxford Nanopore Technologies (ONT). PacBio uses a technology called Single Molecule, Real-Time (SMRT) sequencing, which involves observing the synthesis of DNA in real-time. ONT, on the other hand, involves passing DNA molecules through nanopores and measuring changes in electrical conductivity to determine the sequence of bases.
