How is Long Read Sequencing Applied in Cancer Research?
Long read sequencing is applied in various ways within cancer research:
Whole Genome Sequencing: Researchers can use long read sequencing for whole genome sequencing to obtain a comprehensive view of the cancer genome. Targeted Sequencing: Long reads can be used to sequence specific regions of interest, such as known oncogenes and tumor suppressor genes. Single-Cell Sequencing: Long read sequencing can be applied to single-cell analysis, providing insights into the heterogeneity of cancer and the evolution of tumor cells. Epigenetic Profiling: Long reads can be used to study epigenetic modifications, such as DNA methylation, which play a crucial role in cancer development.