The spindle apparatus forms during prophase when microtubules polymerize from centrosomes. These microtubules attach to chromosomes at the kinetochores located at the centromeres. During metaphase, chromosomes align at the metaphase plate, and during anaphase, sister chromatids are pulled apart to opposite poles of the cell. Finally, during telophase, the cell divides, distributing chromosomes equally to each daughter cell.
