EGFR is an important player in the development and progression of various cancers. Mutations or overexpression of the EGFR gene can lead to uncontrolled cell division and tumor growth. This is particularly evident in cancers such as non-small cell lung cancer (NSCLC), glioblastoma, and colorectal cancer. EGFR mutations are often associated with increased sensitivity to targeted therapies, making them a focal point in cancer treatment.