protein translation

How is Protein Translation Dysregulated in Cancer?

In cancer, several mechanisms can lead to the dysregulation of protein translation. These include:
Mutations in genes encoding translation factors
Overexpression of oncogenic pathways like the mTOR pathway
Altered expression of microRNAs that regulate translation
Changes in the availability of ribosomal proteins
These alterations can result in the selective translation of oncogenes and other proteins that promote cancer progression.

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