HER3 and HER4 are members of the human epidermal growth factor receptor (HER/EGFR) family. This family includes four receptors: HER1 (EGFR), HER2, HER3, and HER4. These receptors play crucial roles in cell growth, differentiation, and survival by activating various intracellular signaling pathways. While HER1 and HER2 have been extensively studied in the context of cancer, HER3 and HER4 are gaining increasing attention due to their unique roles and potential as therapeutic targets.
