Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immune cells that play a crucial role in the immune system. They are known for their potent immunosuppressive activities, which help tumors evade the immune response. MDSCs interfere with T cell activation and proliferation, produce immunosuppressive molecules like arginase and reactive oxygen species, and contribute to the creation of an immunosuppressive tumor microenvironment.
