RAS: Involved in transmitting signals within cells; mutations in RAS are found in various cancers, including pancreatic, lung, and colorectal cancers. MYC: A transcription factor that controls the expression of several genes; overexpression of MYC is associated with many types of cancer. HER2: A receptor tyrosine kinase involved in cell growth and differentiation; amplification of HER2 is seen in some breast cancers.