What are some notable Streptomyces-derived anticancer agents?
Several anticancer agents derived from Streptomyces have been utilized in clinical settings, including:
Doxorubicin: A widely used chemotherapy drug derived from Streptomyces peucetius, effective against a variety of cancers such as breast cancer, ovarian cancer, and lymphomas. Bleomycin: Derived from Streptomyces verticillus, this drug is used to treat Hodgkin's lymphoma, testicular cancer, and other malignancies. Mitomycin C: Produced by Streptomyces caespitosus, it is used in the treatment of upper gastrointestinal cancers and certain types of eye cancers.