What Are the Advantages of Using ISH in Cancer Diagnosis?
ISH offers several advantages in cancer diagnosis: - Localization: It allows for the spatial localization of genetic changes within the tissue architecture. - Sensitivity and Specificity: ISH is highly sensitive and can detect single-copy genes and small genetic alterations with high specificity. - Multiplexing: Especially with FISH, multiple targets can be detected in a single assay, providing comprehensive genetic profiling of the tumor.