What are the Alternatives to Co-Immunoprecipitation?
While Co-IP is a powerful technique, it is not the only method to study protein interactions. Alternatives include: - Yeast Two-Hybrid Screening: A genetic approach to detect protein-protein interactions. - Proximity Ligation Assay: A technique to visualize interactions in situ. - Affinity Purification-Mass Spectrometry (AP-MS): Combines affinity purification of protein complexes with mass spectrometric analysis to identify interacting partners.
