What are the Approved Hedgehog Pathway Inhibitors?
Several Hedgehog pathway inhibitors have received regulatory approval for clinical use. The most notable ones include:
- Vismodegib: Approved for the treatment of advanced basal cell carcinoma. - Sonidegib: Also approved for advanced basal cell carcinoma. - Glasdegib: Approved for use in combination with low-dose cytarabine for the treatment of newly diagnosed acute myeloid leukemia (AML) in adult patients who are not candidates for intensive chemotherapy.
