What are the Challenges in Researching the SWI/SNF Complex?
One of the main challenges in researching the SWI/SNF complex is its structural complexity and the diverse roles of its subunits. Additionally, the context-dependent effects of SWI/SNF mutations make it difficult to generalize findings across different cancer types. Advanced genomic sequencing technologies and functional studies are essential to unravel the complexities of this chromatin remodeling complex.