What Are the Clinical Implications of MRP1 in Cancer Treatment?
The presence of MRP1 in cancer cells is often associated with poor clinical outcomes. High levels of MRP1 expression can correlate with reduced response to chemotherapy and lower survival rates in patients. As a result, MRP1 is considered a potential biomarker for predicting drug resistance and prognosis. Understanding the role of MRP1 in cancer can help in developing strategies to overcome drug resistance, such as using MRP1 inhibitors in combination with standard chemotherapy.