What Are the Future Directions for Research on HLA Class II in Cancer?
Future research on HLA Class II in cancer aims to overcome current challenges and enhance therapeutic applications. This includes developing strategies to increase HLA Class II expression selectively on tumor cells, understanding the mechanisms of immune evasion by tumors, and exploring the genetic basis of HLA-related cancer susceptibility. Advances in genomic technologies and bioinformatics will facilitate the identification of novel HLA-associated biomarkers for cancer prognosis and treatment response. Additionally, research into the interactions between HLA Class II and other immune-regulatory molecules may uncover new avenues for combination therapies.
