What are the Implications of Genomic Instability in Cancer Treatment?
Genomic instability in cancer cells presents both challenges and opportunities for treatment. On the one hand, it can lead to resistance to therapies due to the high mutation rate. On the other hand, targeting the specific mutations or exploiting the inherent weaknesses of cancer cells, such as their reliance on certain DNA repair pathways, can be effective strategies. For example, PARP inhibitors are used to target cancers with BRCA mutations.
