What Are the Limitations of Using Restricted Diffusion?
While restricted diffusion is a powerful tool, it has its limitations: - Non-Specificity: Restricted diffusion can occur in non-cancerous conditions such as abscesses or inflammation, leading to potential false positives. - Technical Challenges: Image artifacts and variations in scanning protocols can affect the accuracy of DWI and ADC measurements. - Tumor Heterogeneity: Not all tumor types exhibit restricted diffusion uniformly, which may complicate interpretation.
