What are the Mechanisms Behind Polyuria in Cancer?
The mechanisms leading to polyuria in cancer patients include:
Direct Tumor Effects: Tumors in the urinary system can interfere with normal urine storage and release. Treatment Side Effects:Chemotherapy and radiation therapy can damage the kidneys or bladder, leading to polyuria. Paraneoplastic Syndromes: Some cancers produce hormones or other substances that affect urine production, such as antidiuretic hormone. Metabolic Effects: Conditions like hypercalcemia (high calcium levels) are common in certain cancers and can cause polyuria.