polyuria (increased urine output)

What are the Mechanisms Behind Polyuria in Cancer?

The mechanisms leading to polyuria in cancer patients include:
Direct Tumor Effects: Tumors in the urinary system can interfere with normal urine storage and release.
Treatment Side Effects: Chemotherapy and radiation therapy can damage the kidneys or bladder, leading to polyuria.
Paraneoplastic Syndromes: Some cancers produce hormones or other substances that affect urine production, such as antidiuretic hormone.
Metabolic Effects: Conditions like hypercalcemia (high calcium levels) are common in certain cancers and can cause polyuria.

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