What Are the Molecular Mechanisms Behind Metastasis?
Metastasis involves a series of steps where cancer cells spread from the primary tumor to distant sites. Key molecular mechanisms include epithelial-mesenchymal transition (EMT), where cancer cells gain migratory and invasive properties, and the interaction with the extracellular matrix (ECM). Proteins like E-cadherin and N-cadherin play significant roles in these processes.
