What are the Therapeutic Implications of Desmoplasia?
Targeting desmoplasia presents both challenges and opportunities for cancer therapy. Therapies aimed at modifying the tumor stroma to reduce fibrosis and improve drug delivery are being actively researched. For example, enzymatic degradation of ECM components using agents like hyaluronidase has shown promise in preclinical studies. Additionally, anti-fibrotic drugs and agents that inhibit stromal cell activation are being explored to enhance the effectiveness of conventional treatments.
