Treatment for GTN depends on the type and stage of the disease. The mainstay of treatment is chemotherapy, which is highly effective for most cases of GTN. Low-risk cases are often treated with single-agent chemotherapy, such as methotrexate or actinomycin-D. High-risk cases may require multi-agent chemotherapy regimens. Surgery, including hysterectomy, may be necessary for persistent disease or in cases where fertility preservation is not a concern. In some instances, radiation therapy may be used if there is metastasis to the brain.
