What Challenges Contribute to Limited Penetration Depth?
Several factors contribute to the challenge of limited penetration depth in cancer: 1. Tumor Microenvironment: The dense extracellular matrix and abnormal blood vessels in tumors impede the diffusion of therapeutic agents. 2. Size and Charge of Molecules: Large or highly charged molecules often struggle to penetrate deep tissues. 3. Hypoxia: Low oxygen levels in tumors can affect the effectiveness of certain therapies, such as radiation.
