Several factors contribute to the metastatic potential of cancer cells:
1. Genetic Mutations: Changes in certain genes can enhance a cell's ability to spread. 2. Microenvironment: The surrounding environment of the primary tumor can influence how easily cancer cells can invade other tissues. 3. Immune System Evasion: Cancer cells can sometimes avoid detection and destruction by the immune system, allowing them to survive and spread. 4. Angiogenesis: The formation of new blood vessels can supply the growing tumor with the necessary nutrients and oxygen, facilitating further growth and spread.