Human Herpesvirus 8 (HHV-8), also known as Kaposi's Sarcoma-associated Herpesvirus (KSHV), is a member of the herpesvirus family. It is primarily known for its association with Kaposi's Sarcoma (KS), a type of cancer that forms in the lining of blood and lymph vessels. HHV-8 is a double-stranded DNA virus that can integrate into the host's genome, leading to latent and lytic infections.