What is Major Histocompatibility Complex (MHC) Class I?
The Major Histocompatibility Complex (MHC) Class I molecules are essential components of the immune system. They are found on the surface of almost all nucleated cells and play a crucial role in presenting endogenous peptides, including those derived from intracellular pathogens or abnormal cell activity, to cytotoxic T lymphocytes (CTLs). This presentation is essential for the immune system to recognize and eliminate infected or malignant cells.
