What is Senescence Associated Secretory Phenotype (SASP)?
The Senescence Associated Secretory Phenotype (SASP) refers to the phenomenon where senescent cells, which have ceased to divide, begin to secrete a variety of pro-inflammatory cytokines, chemokines, growth factors, and proteases. This secretory phenotype can have profound effects on the tissue microenvironment, influencing processes such as inflammation, tissue repair, and even tumor progression.
